Article

Patrick, Shruti and Gowda, Pruthvi and Lathoria, Kirti and Suri, Vaishali and Sen, Ellora (2021) YAP1-mediated regulation of mitochondrial dynamics in IDH1 mutant gliomas. Journal of Cell Science, 134 (22). jcs259188. ISSN 0021-9533

Gowda, Pruthvi and Lathoria, Kirti and Umdor, Sonia B and Sen, Ellora (2021) Brg1 mutation alters oxidative stress responses in glioblastoma. Neurochemistry International, 150. p. 105189. ISSN 01970186 (In Press)

Gowda, Pruthvi and Patrick, Shruti and Joshi, Shanker Datt and Kumawat, Rajesh Kumar and Sen, Ellora (2021) Glycyrrhizin Prevents Sars-Cov-2 S1 and Orf3a Induced High Mobility Group Box 1 (Hmgb1) Release and Inhibits Viral Replication. Cytokine, 142 (155496).

Gowda, Pruthvi and Patrick, Shruti and Joshi, Shanker Datt and Kumawat, Rajesh Kumar and Sen, Ellora (2021) Repurposing Methotrexate in Dampening SARS-CoV2-S1-Mediated IL6 Expression: Lessons Learnt from Lung Cancer. Inflammation, 45 (1). pp. 172-179. ISSN 0360-3997

Gowda, Pruthvi and Lathoria, Kirti and Sharma, Shalini and Patrick, Shruti and Umdor, Sonia B and Sen, Ellora (2021) Rewiring of Lactate-Il-1beta Auto-Regulatory Loop with Clock-Bmal1: A Feed-Forward Circuit in Glioma. Mol Cell Biol (MCB004).

Shelkh, Touseef and Sen, Ellora (2021) p53 affects epigenetic signature on SOCS1 promoter in response to TLR4 inhibition. Cytokine (140). p. 155418.

Gowda, P and Patrick, S and Singh, A and Sheikh, T and Sen, Ellora (2018) Mutant Isocitrate Dehydrogenase 1 Disrupts PKM2–β-Catenin–BRG1 Transcriptional Network-Driven CD47 Expression. Molecular and Cellular Biology , 38 (9). e00001-18.

Sheikh, T and Gupta, P and Gowda, P and Patrick, S and Sen, Ellora (2018) Hexokinase 2 and nuclear factor erythroid 2-related factor 2 transcriptionally coactivate xanthine oxidoreductase expression in stressed glioma cells. J Biol Chem, 293 (13). pp. 4767-4777.

Ahmad, Fahim and Patrick, Shruti and Sheikh, Touseef and Sharma, Vikas and Pathak, Pankaj and Malgulwar, Prit Benny and Kumar, Anupam and Joshi, Shanker Datt and Sarkar, C and Sen, Ellora (2017) Telomerase reverse transcriptase (TERT) - enhancer of zeste homolog 2 (EZH2) network regulates lipid metabolism and DNA damage responses in glioblastoma. J Neurochem., 143 (6). pp. 671-683.

Singh, A and Sen, Ellora (2017) Reciprocal role of SIRT6 and Hexokinase 2 in the regulation of autophagy driven monocyte differentiation. Exp Cell Res, 360 (2). pp. 365-374.

Majumdar, Atreye and Ahmad, Fahim and Sheikh, Touseef and Bhagat, Reshma and Pathak, Pankaj and Joshi, Shanker Datt and Seth, Pankaj and Tandon, Vivek and Tripathi, Manjari and Sarat Chandra, P. and Sarkar, Chitra and Sen, Ellora (2017) miR-217-casein kinase-2 cross talk regulates ERK activation in ganglioglioma. J Mol Med (Berl), 95 (11). pp. 1215-1226.

Gupta, P and Sheikh, T and Sen, Ellora (2017) SIRT6 regulated nucleosomal occupancy affects Hexokinase 2 expression. Exp Cell Res, 357 (1). pp. 98-106.

Ghosh, S and Gupta, P and Sen, Ellora (2016) TNFα driven HIF-1α-hexokinase II axis regulates MHC-I cluster stability through actin cytoskeleton. Exp Cell Res, 340 (1). pp. 116-124.

Gupta, P and Singh, A and Gowda, P and Ghosh, S and Chatterjee, A and Sen, Ellora (2016) Lactate induced HIF-1α-PRMT1 cross talk affects MHC I expression in monocytes. Experimental Cell Research, 347 (2). pp. 293-300.

Ahmad, Fahim and Dixit, Deobrat and Joshi, Shanker Datt and Sen, Ellora (2016) G9a inhibition induced PKM2 regulates autophagic responses. The International Journal of Biochemistry & Cell Biology, 78. pp. 87-95.

Dixit, Deobrat and Ahmad, Fahim and Ghildiyal, Ruchi and Joshi, Shanker Datt and Sen, Ellora (2016) CK2 inhibition induced PDK4-AMPK axis regulates metabolic adaptation and survival responses in glioma. Exp Cell Res, 344 (1). pp. 132-142.

Ahmad, Fahim and Dixit, Deobrat and Sharma, V and Kumar, A and Joshi, Shanker Datt and Sarkar, C and Sen, Ellora (2016) Nrf2-driven TERT regulates pentose phosphate pathway in glioblastoma. Cell Death Dis, 7. e2213.

Ghildiyal, R and Sen, Ellora (2015) Concerted action of histone methyltransferases G9a and PRMT-1 regulates PGC-1α-RIG-I axis in IFNγ treated glioma cells. Cytokine, 89. pp. 185-193.

Ghildiyal, R and Sen, Ellora (2015) CK2 induced RIG-I drives metabolic adaptations in IFNc-treated glioma cells. Cytokine, 89. pp. 219-228.

Chatterjee, A and Mondal, P and Ghosh, S and Mehta, VS and Sen, Ellora (2015) PPARγ regulated CIDEA affects pro-apoptotic responses in glioblastoma. Cell Death Discov, 1. p. 15038.

Ahmad, Fahim and Ghosh, Sadashib and Sinha, Sanchari and Joshi, Shanker Datt and Mehta, Veer Singh and Sen, Ellora (2015) TGF-β-induced hCG-β regulates redox homeostasis in glioma cells. Mol Cell Biochem, 399 (1-2). pp. 105-112.

Dixit, D and Ghildiyal, R and Anto, NP and Sen, Ellora (2014) Chaetocin-induced ROS-mediated apoptosis involves ATM-YAP1 axis and JNK-dependent inhibition of glucose metabolism. Cell Death Dis, 8 (5). p. 1212.

Gupta, P and Ghosh, S and Nagarajan, A and Sen, Ellora (2013) β-defensin-3 negatively regulates TLR4-HMGB1 axis mediated HLA-G expression in IL-1β treated glioma cells. Cell Signal, 25 (3). pp. 682-689.

Ugir Hossain, SK and Dixit, D and Sen, Ellora (2013) Comparative study of microtubule inhibitors- Estramustine and natural Podophyllotoxin conjugated PAMAM dendrimer on glioma cell proliferation. Eur J Med Chem, 68. pp. 47-57.

Dixit, D and Ghildiyal, R and Anto, NP and Ghosh, S and Sharma, V and Sen, Ellora (2013) Guggulsterone sensitizes glioblastoma cells to Sonic hedgehog inhibitor SANT-1 induced apoptosis in a Ras/NFκB dependent manner. Cencer Lett, 336 (2). pp. 347-358.

Ghosh, S and Paul, A and Sen, Ellora (2013) Tumor necrosis factor α-induced hypoxia-inducible factor 1α-β-catenin axis regulates major histocompatibility complex class I gene activation through chromatin remodeling. Mol Cell Biol, 33 (14). pp. 2718-2731.

Sinha, S and Ghildiyal, R and Mehta, VS and Sen, Ellora (2013) ATM-NFKB axis driven TIGAR regulates sensitivity of glioma cells to radiomimetics in the presence of TNFα. Cell Death Dis, 4 (5). p. 615.

Ghildiyal, R and Dixit, D and Sen, Ellora (2013) EGFR inhibitor BIBU induces apoptosis and defective autophagy in glioma cells. Mol Carcinog, 52 (12). pp. 970-982.

Gupta, P and Dixit, D and Sen, Ellora (2012) Oncrasin Targets the JNK-NF-κB Axis to Sensitize Glioma Cells to TNFα-induced Apoptosis. Carciongenesis, 34 (2). pp. 388-396.

Tewari, R and Choudhury, SR and Mehta, VS and Sen, Ellora (2012) TNFα regulates the localization of CD40 in lipid rafts of glioma cells. Mol Bio Rep, 39 (9). pp. 8695-8699.

Tewari, R and Choudhury, SR and Ghosh, S and Metha, VS and Sen, Ellora (2012) Involvement of TNFα-induced TLR4-NF-κB and TLR4-HIF-1α feed-forward loops in the regulation of inflammatory responses in glioma. J Mol Med (Berl), 90 (1). pp. 67-80.

Dixit, D and Sharma, V and Ghosh, S and Mehta, VS and Sen, Ellora (2012) Inhibition of Casein kinase-2 induces p53-dependent cell cycle arrest and sensitizes glioblastoma cells to tumor necrosis factor (TNFα)-induced apoptosis through SIRT1 inhibition. Cell Death Dis, 3 (e271).

Sen, Ellora and Basu, Anirban and Willing, Lisa B and Uliasz, Tracy F and Myrkalo, Jaimie L and Vannucci, Susan J and Hewett, Sandra J and Levison, Steven W (2011) Pre-conditioning induces the precocious differentiation of neonatal astrocytes to enhance their neuroprotective properties. Neuro Research, 3 (3).

Sharma, V and Dixit, D and Ghosh, S and Sen, Ellora (2011) COX-2 regulates the proliferation of glioma stem like cells. Neurochemistry International, 59. pp. 567-571.

Sharma, V and Shaheen, SS and Dixit, D and Sen, Ellora (2011) Farnesyltransferase inhibitor manumycin targets IL1β-Ras-HIF-1α axis in tumor cells of diverse origin. Inflammation, 35 (2). pp. 516-519.

Sinha, Sanchari and Koul, N and Dixit, D and Sharma, V and Sen, Ellora (2011) IGF-1 induced HIF-1α-TLR9 cross talk regulates inflammatory responses in glioma. Cellular Signalling, 23. pp. 1869-1875.

Sharma, V and Dixit, D and Koul, N and Mehta, VS and Sen, Ellora (2011) Ras regulates interleukin-1β-induced HIF-1α transcriptional activity in glioblastoma. J Mol Med, 89. pp. 123-136.

Sen, Ellora (2011) Targeting inflammation-induced transcription factor activation: an open frontier for glioma therapy. Drug Discovery Today, 16. pp. 1044-1051.

Sharma, V and Koul, N and Joseph, C and Dixit, D and Ghosh, S and Sen, Ellora (2010) HDAC inhibitor, scriptaid, induces glioma cell apoptosis through JNK activation and inhibits telomerase activity. Journal of Cellular and Molecular Medicine, 14 (8). pp. 2151-2161.

Bain, JM and Ziegler, A and Yang, Z and Levison, SW and Sen, Ellora (2010) TGFß1 Stimulates the Over-Production of White Matter Astrocytes from Precursors of the “Brain Marrow” in a Rodent Model of Neonatal Encephalopathy. PLoS One.

Koul, N and Sharma, V and Dixit, D and Ghosh, S and Sen, Ellora (2010) Bicyclic triterpenoid Iripallidal induces apoptosis and inhibits Akt/mTOR pathway in glioma cells. BMC Cancer, 10 (328).

Ghosh, S and Tewari, R and Dixit, D and Sen, Ellora (2010) TNFalpha induced oxidative stress dependent Akt signaling affects actin cytoskeletal organization in glioma cells. Neurochem Int, 56 (1). pp. 194-201.

Tewari, R and Sharma, V and Koul, N and Ghosh, A and Joseph, C and Hossain, SKU and Sen, Ellora (2009) Ebselen Abrogates Tnfalpha Induced Pro-Inflammatory Response in Glioblastoma. Mol Oncol, 3 (1). pp. 77-83.

Dixit, D and Sharma, V and Ghosh, S and Koul, N and Mishra, PK and Sen, Ellora (2009) Manumycin inhibits STAT3, telomerase activity, and growth of glioma cells by elevating intracellular reactive oxygen species generation. Free Radical Biology & Medicine, 47 (4). pp. 364-374.

Sharma, V and Tewari, R and Ugir Hossain, SK and Joseph, C and Sen, Ellora (2008) Ebselen sensitizes glioblastoma cells to Tumor Necrosis Factor (TNFalpha)-induced apoptosis through two distinct pathways involving NF-kappaB downregulation and Fas-mediated formation of death inducing signaling complex. International Journal of Cancer, 123 (9). pp. 2204-2212.

Tewari, R and Sharma, V and Koul, N and Sen, Ellora (2008) Involvement of miltefosine-mediated ERK activation in glioma cell apoptosis through Fas regulation. J Neurochem, 107 (3). pp. 616-627.

Agarwal, A and Sharma, V and Tewari, R and Koul, N and Joseph, C and Sen, Ellora (2008) Epigallocatechin-3-gallate exhibits anti-tumor effect by perturbing redox homeostasis, modulating the release of pro-inflammatory mediators and decreasing the invasiveness of glioblastoma cells. Mol Med Rep, 1 (4). pp. 511-515.

Sen, Ellora (2007) On the Lives of Stars and Cells. Current Science, 92 (8). pp. 1041-1042.

Sharma, V and Joseph, C and Ghosh, S and Agarwal, A and Mishra, MK and Sen, Ellora (2007) Kaempferol induces apoptosis in glioblastoma cells through oxidative stress. AACR, 6 (9). pp. 2544-2553.

Sharma, Vivek and Mishra, Mamata and Ghosh, Soumya and Tewari, Richa and Basu, Anirban and Seth, Pankaj and Sen, Ellora (2007) Modulation of interleukin-1beta mediated inflammatory response in human astrocytes by flavonoids: implications in neuroprotection. Brain Research Bull, 73 (1_3). pp. 55-63.

Ghoshal, Ayan and Das, Sulagna and Ghosh, Soumya and Mishra, Manoj Kumar and Sharma, Vivek and Koli, Preeti and Sen, Ellora and Basu, Anirban (2007) Proinflammatory mediators released by activated microglia induces neuronal death in Japanese encephalitis. GLIA, 55 (5). pp. 483-496.

Sen, Ellora and Levison, SW (2006) Astrocytes and developmental white matter disorders. Ment Retard Dev Disabil Res Rev, 12 (2). pp. 97-104.

Book Section

Sen, Ellora (2013) The Philosophical Quest of a Cancer Cell: Redefining Existentialism. In: Evolution-adjusted Tumor Pathophysiology: The Novel Language of Tumor Biology. Springer, pp. 145-154.