Article

Maheshwari, M and Bhutani, S and Das, A and Mukherjee, R and Sharma, A and Kino, Y and Nukina, N and Jana, NR (2014) Dexamethasone induces heat shock response and slows down disease progression in mouse and fly models of Huntington's disease. Hum Mol Genet., 23 (10). pp. 2737-2751.

Godavarthi, SK and Narender, D and Mishra, A and Goswami, A and Rao, SN and Nukina, N and Jana, NR (2009) Induction of chemokines, MCP-1, and KC in the mutant huntingtin expressing neuronal cells because of proteasomal dysfunction. Journal of Neurochemistry, 108 (3). pp. 787-795.

Mishra, A and Dikshit, P and Purkayastha, S and Sharma, J and Nukina, N and Jana, NR (2008) E6-AP promotes misfolded polyglutamine proteins for proteasomal degradation and suppresses polyglutamine protein aggregation and toxicity. THE JOURNAL OF BIOLOGICAL CHEMISTRY, 283 (12). pp. 7648-7656.

Dikshit, P and Goswami, A and Mishra, A and Nukina, N and Jana, NR (2006) Curcumin enhances the polyglutamine-expanded truncated N-terminal huntingtin-induced cell death by promoting proteasomal malfunction. Biochem Biophys Res Commun, 342 (4). pp. 1323-1328.

Goswami, A and Dikshit, P and Mishra, A and Mulherkar, S and Nukina, N and Jana, NR (2006) Oxidative stress promotes mutant huntingtin aggregation and mutant huntingtin-dependent cell death by mimicking proteasomal malfunction. Biochem Biophys Res Commun, 342 (2). pp. 184-190.

Goswami, A and Dikshit, P and Mishra, A and Nukina, N and Jana, NR (2006) Expression of expanded polyglutamine proteins suppresses the activation of transcription factor NFkappaB. THE JOURNAL OF BIOLOGICAL CHEMISTRY, 281 (48). pp. 37017-37024.

Jana, NR and Nukina, N (2005) BAG-1 associates with the polyglutamine-expanded huntingtin aggregates. Neurosci Lett, 378 (3). pp. 171-175.

Jana, NR and Dikshit, P and Goswami, A and Kotliarova, S and Murata, S and Tanaka, K and Nukina, N (2005) Co-chaperone CHIP associates with expanded polyglutamine protein and promotes their degradation by proteasomes. THE JOURNAL OF BIOLOGICAL CHEMISTRY, 280 (12). pp. 11635-11640.

Jana, NR and Nukina, N (2004) Assessment of impaired proteasomal function in a cellular model of polyglutamine diseases. Methods Mol Biol, 277. pp. 287-292.

Jana, NR and Dikshit, P and Goswami, A and Nukina, N (2004) Inhibition of proteasomal function by curcumin induces apoptosis through mitochondrial pathway. THE JOURNAL OF BIOLOGICAL CHEMISTRY, 279 (12). pp. 11680-11685.

Jana, NR and Nukina, N (2004) Misfolding promotes the ubiquitination of polyglutamine-expanded ataxin-3, the defective gene product in SCA3/MJD. Neurotox Res, 6 (7-8). pp. 523-533.

Jana, NR and Nukina, N (2003) Recent advances in understanding the pathogenesis of polyglutamine diseases: involvement of molecular chaperones and ubiquitin-proteasome pathway. J Chem Neuroanat, 26 (2). pp. 95-101.