Amanullah, A and Upadhyay, A and Joshi, V and Mishra, R and Jana, NR and Mishra, A (2017) Progressing neurobiological strategies against proteostasis failure: Challenges in neurodegeneration. Progress in Neurobiology, 159. pp. 1-38.

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Abstract

Proteins are ordered useful cellular entities, required for normal health and organism’s survival. The proteome is the absolute set of cellular expressed proteins, which regulates a wide range of physiological functions linked with all domains of life. In aging cells or under unfavorable cellular conditions, misfolding of proteins generates common pathological events linked with neurodegenerative diseases and aging. Current advances of proteome studies systematically generates some progress in our knowledge that how misfolding of proteins or their accumulation can contribute to the impairment or depletion of proteome functions. Still, the underlying causes of this unrecoverable loss are not clear that how such unsolved transitions give rise to multifactorial challengeable degenerative pathological

Item Type:	Article
Subjects:	Neurodegenerative Disorders Neuro-Oncological Disorders Neurocognitive Processes Neuronal Development and Regeneration Informatics and Imaging Genetics and Molecular Biology
Depositing User:	Dr. D.D. Lal
Date Deposited:	11 Sep 2018 11:31
Last Modified:	11 Sep 2018 11:31
URI:	http://nbrc.sciencecentral.in/id/eprint/441

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