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Cheng, W and Xiaojing, C and Heekyung, L and Deshmukh, SS and Doreswamy, Y and Francesco, S and Knierim, JJ (2018) Egocentric coding of external items in the lateral entorhinal cortex. Neuroscience, 362 (6417). pp. 945-949.

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Abstract

Episodic memory, the conscious recollection of past events, is typically experienced from a first-person (egocentric) perspective. The hippocampus plays an essential role in episodic memory and spatial cognition. Although the allocentric nature of hippocampal spatial coding is well understood, little is known about whether the hippocampus receives egocentric information about external items. We recorded in rats the activity of single neurons from the lateral entorhinal cortex (LEC) and medial entorhinal cortex (MEC), the two major inputs to the hippocampus. Many LEC neurons showed tuning for egocentric bearing of external items, whereas MEC cells tended to represent allocentric bearing. These results demonstrate a fundamental dissociation between the reference frames of LEC and MEC neural representations.

Item Type: Article
Subjects: Neurodegenerative Disorders
Neuro-Oncological Disorders
Neurocognitive Processes
Neuronal Development and Regeneration
Informatics and Imaging
Genetics and Molecular Biology
Depositing User: Dr. D.D. Lal
Date Deposited: 10 Dec 2018 09:21
Last Modified: 12 Mar 2020 06:11
URI: http://nbrc.sciencecentral.in/id/eprint/490

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