Budhachandra, KH and Brojen Singh, RK and Menon, GI (2008) Microtubule Dynamics Regulated by Stathmin. Comput Biol Chem, 32 (2). pp. 141-144.

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Abstract

Microtubules perform a variety of functions which lead to the complex regulation of intracellular transport and cell division. However, the regulation of microtubule growth is not clearly known. Based on a recent experimental finding, we explore the possibility of spatial regulation of microtubule growth by stathmin–tubulin interaction gradients. Computer simulation of the model with stathmin–tubulin interaction gradients gave regulated growth as seen in experiments. In future, the stathmin–tubulin interaction gradients can be made dynamic and its impact on the microtubule growth can be explored.

Item Type:	Article
Subjects:	Neurodegenerative Disorders Neuro-Oncological Disorders Neurocognitive Processes Neuronal Development and Regeneration Informatics and Imaging Genetics and Molecular Biology
Depositing User:	Dr. D.D. Lal
Date Deposited:	11 Feb 2020 06:53
Last Modified:	11 Feb 2020 06:53
URI:	http://nbrc.sciencecentral.in/id/eprint/594

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