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Ranade, SC (2015) Nutrition and Developmental Programming of Central Nervous System (CNS). In: Handbook of Fertility. Academic Press, pp. 241-252.

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Many neurological disorders, neurodegenerative diseases, and psychiatric pathologies can be traced back to their in utero origins. Recent research advances have demonstrated the strong role of nutrition as a modulator. Any deviations from the optimum, such as undernutrition or overnutrition or the absence or excess of any nutritional factor in the diet, constitute nutritional insult. Since these nutritional perturbations are encountered during the formative period, the effects remain long-lasting and mostly irreversible. Early life malnutrition therefore is known to have lasting effects on the developing nervous system predisposing the fetus to the risk of late onset neurological disorders or psychiatric illnesses. In this chapter, we will discuss the developmental programming of the brain with respect to the types of nutritional deficiencies, their effects on the central nervous system, and critical developmental windows of susceptibility, mechanism of action and rehabilitation or intervention therapies.

Item Type: Book Section
Subjects: Neurodegenerative Disorders
Neuro-Oncological Disorders
Neurocognitive Processes
Neuronal Development and Regeneration
Informatics and Imaging
Genetics and Molecular Biology
Depositing User: Dr. D.D. Lal
Date Deposited: 17 Sep 2018 04:17
Last Modified: 17 Sep 2018 04:17
URI: http://nbrc.sciencecentral.in/id/eprint/463

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